Scientific Program (confirmed speakers and chairs)

Scientific sessions cover a wide range of topics in the P-type ATPase field with presentations by world leading scientists.

Opening Remarks:Giuseppe InesiCalifornia Pacific Medical Center
Special Lecture:Toshio AndoKanazawa Univ.
Nano-visualization of protein molecules in action by high-speed AFM
Keynote Lectures:Poul NissenAarhus Univ.
Chikashi ToyoshimaUniv. of Tokyo

1. Na,K-ATPase and H,K-ATPase 1 (structure-function relationship)

Chair: Flemming CorneliusAarhus Univ.
Kazuhiro AbeNagoya Univ.
Structural and functional analysis of gastric H+,K+-ATPase
Ronald ClarkeUniv. of Sydney
Role of electrostatic stabilisation in the mechanism and regulation of Na+,K+- and H+,K+-ATPases
David GadsbyRockfeller Univ.
Proton import by Na/K pumps: evolutionary limit, or hybrid function possibly linked to neurological disorders?
Haruo OgawaUniv. of Tokyo
Bente VilsenAarhus Univ.
New aspects of sodium and potassium binding of Na,K-ATPase

2. Na,K-ATPase and H,K-ATPase 2 (physiology and diseases)

Chair: Kathleen SweadnerMassachusetts General Hospital
Anita AperiaKarolinska Institute
Na,K-ATPase, a non-canonical signal transducer
Minako HoshiKyoto Univ.
Na, K-ATPase 3 and Alzheimer's Disease
Steve KarlishWeizmann Institute
Kiyoshi KawakamiJichi Medhical Univ.
Atp1a2-deficient mice as a model of familial hemiplegic migraine
Helge RasmussenUniv. of Sydney
Na-K pump stimulation and FXYD3 suppression as treatment objectives in heart failure and cancer
Zijian XieMarshall Univ.

3. Ca-ATPase and other P2-ATPases

Chair: Giuseppe InesiCalifornia Pacific Medical Center
Rajini RaoJohns Hopkins Univ.
Hiroshi SuzukiAsahikawa Medical Univ.
Structure/function of Ca-ATPase revealed by mutations, kinetics, and structural analyses of reaction intermediates
David D. ThomasUniversity of Minnesota

4. Pump regulators

Chair: Howard S. YoungUniv. of Alberta
Muthu PeriasamySunford Burnham Prebys, Medical Discovery Institute
Seth RobiaLoyola Univ. Chicago
Howard S. YoungUniv. of Alberta

5. P4-ATPase (Flippase) - structure, function, cell biology and disease

Chair: Todd R. GrahamVanderbilt Univ.
Jens Peter AndersenAarhus Univ.
Mutagenesis of ATP8A2: On the track of the lipid transport pathway.
Todd R. GrahamVanderbilt Univ.
Novel substrates and transport mechanisms for P4-ATPases
Guillaume LenoirInstitute for Integrative Biology of the Cell
Katsumori SegawaOsaka Univ.
Function and regulation of plasma membrane phospholipid flippases
Hye-won ShinKyoto Univ.
Specific substrates for P4-ATPases and their regulation in mammalian cells

6. Other P-type ATPases including P1, P5-ATPases

Chair: Jack KaplanUniv. of Illinois at Chicago
Jose M. ArguelloWocester Polytechnic Institute
Svetlana LutsenkoJohns Hopkins Univ
Michael PalmgrenUniv. of Copenhagen
Evolution and role of zinc pumps in eukaryotes
David StokesNew York Univ.
Peter VangheluweKU Leuven
Novel P-type ATPases as gatekeepers of neuronal health

7. Molecular simulations - towards quantitative understanding

Chair: Yuji SugitaRIKEN
Himanshu KhandeliaUniv. of Southern Denmark
The elusive proton in ion pumps
Yuji SugitaRIKEN

8. Emerging technologies

Chair: Takayuki NishizakaGakusyuin Univ.
Takayuki NishizakaGakusyuin Univ.
Application of single-molecule techniques to supramolecular machinery in bacteria and archaea
Rikiya WatanabeUniv. of Tokyo
Novel microsystems for highly sensitive analysis of transport proteins